![]() ![]() Our results indicate that sensing of N-acetyl- D-glucosamine induces GibS expression, which in turn modifies the transcript levels of metabolic enzymes.īacteroides are Gram-negative, obligate anaerobic, non-motile, non-spore forming rods, and among the most abundant bacterial genera in the human intestine 1. We use computational predictions and experimental data to determine the secondary structure of GibS and identify its target genes. Among the latter is GibS, a conserved, 145 nt-long small RNA that is highly expressed in the presence of N-acetyl- D-glucosamine as sole carbon source. ![]() An online browser, called ‘Theta-Base’ ( is launched to interrogate the obtained gene expression data and annotations of ~4500 transcription start sites, untranslated regions, operon structures, and 269 noncoding RNA elements. thetaiotaomicron grown under defined laboratory conditions. Here, we use differential RNA sequencing (dRNA-seq) to generate a single-nucleotide resolution transcriptome map of B. Among them, the species Bacteroides thetaiotaomicron has emerged as the model organism for functional microbiota research. Bacteria of the genus Bacteroides are common members of the human intestinal microbiota and important degraders of polysaccharides in the gut. ![]()
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